To begin, pat the pork loin dry and combine all spices together in a small bowl.
Season the pork loin generously on all sides with the seasoning blend. Place into a large Crockpot or slow cooker.
Cook on low for 5-6 hours, or high for 3-4 hours. The internal temperature should reach 155 degrees when finished.
Allow the pork to rest for 10-15 minutes at room temperature before slicing to remain moisture.